DIS: Barkhof/Tintoré 2005 versus Swanton 2010
In past versions of the McDonald Criteria, DIS was based on the Barkhof/Tintoré criteria. These criteria were difficult to apply consistently by non-imaging specialists.
The Swanton-based 2010 DIS criteria were shown to be simpler and slightly more sensitive than the original McDonald Criteria for DIS, without compromising the specificity and accuracy.